pE-4000 Flexible 4-Channel Microscopy Illumination System
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Ships from:
United Kingdom
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On FindLight:
since 2020
Description
Experience unparalleled flexibility in microscopy illumination with the pE-4000 from CoolLED. Designed to provide optimal illumination, this advanced system enhances the fluorescence of cells while minimizing photobleaching and phototoxicity. The pE-4000 is engineered for precision, offering microsecond switching and variable pulse duration to ensure that your experiments are conducted with the utmost accuracy and efficiency.
With a focus on sustainability, the pE-4000 boasts market-leading energy efficiency. It consumes significantly less power compared to traditional LED technologies, with a maximum power consumption of just 60 W when all four channels are engaged. This not only reduces operational costs but also extends the lifetime of the system, making it a reliable choice for long-term use. The pE-4000 is equipped with award-winning single-chip LED technology, ensuring stable and repeatable performance.
The pE-4000 offers a unique wavelength grouping concept, allowing you to choose from 256 wavelength combinations across 16 installed LEDs. This flexibility enables you to select the optimum wavelength for your specific experiment, enhancing the control over cell responses. The system's advanced controllability allows for precise excitation of individual channels, significantly reducing photobleaching and phototoxicity, as highlighted by Dr. Yan Gu from the University of Sussex.
Designed to fit all major research and clinical microscopes, the pE-4000 delivers light through a liquid light guide or fiber, offering inline removable excitation filter holders for added convenience. The system's adaptability is further enhanced by the Universal Collimator, ensuring seamless integration into your existing setup. With a three-year warranty and a first-year warranty swap, the pE-4000 guarantees reliability and peace of mind, backed by CoolLED's experience and quality assurance processes.
pE-4000 Flexible 4-Channel Microscopy Illumination System
Specifications |
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|---|---|
| Emission Spectral Range: | 365 – 770 nm |
| Application: | Microscopy |
| Channels: | 4 |
| Selectable Wavelengths: | 16 |
| Standby Power Consumption: | Max 7 W |
| Single Wavelength Power Consumption: | Max 25 W |
| Dual Wavelength Power Consumption: | Max 44 W |
| Triple Wavelength Power Consumption: | Max 53 W |
| Quad Wavelength Power Consumption: | Max 60 W |
| Wavelength Combinations: | 256 |
Features
- Flexible Microscopy Illumination: The pE-4000 offers optimal illumination control to extend fluorescence of cells, reduce photobleaching, and minimize phototoxicity. It features microsecond switching and variable pulse duration for precise control.
- Cell Viability: Experience the lowest power consumption compared to other LED technologies, with a long lifetime and highly stable, repeatable award-winning single chip LED technology. Benefit from market-leading energy efficiency.
- Sustainability: Choose from 256 wavelength combinations from 16 installed LEDs (365 nm-770 nm). Select 1 of 4 wavelengths for each of 4 channels on the control pod, utilizing a unique wavelength grouping concept for optimal experiment conditions.
- Selectability: The pE-4000 allows for multiple experiments with varying wavelengths on the same sample, providing specific wavelength characterization for optimal optogenetic control of cell responses.
- Adaptability: Fits all major research and clinical microscopes, delivering light through a liquid light guide or fiber. It offers inline removable excitation filter holders and uses the Universal Collimator.
- Reliability: Benefit from a 3-year warranty with a first-year warranty swap, backed by experience and QA assured processes.
- Controllability: Advanced integration into major systems allows for precise control over individual channels, optimizing excitation intensity to reduce photobleaching and phototoxicity in live experiments.
Applications
- Live-Cell Imaging: Minimize phototoxicity for extended experiments up to 100+ hours.
- Optogenetics: Precise control of excitation wavelengths for optogenetic manipulation of cellular responses.
- Fluorescence Microscopy: Supports multiple fluorophores, including DAPI, FITC, TRITC, and Cy5.
- Multi-Experiment Flexibility: Allows varying wavelength experiments on the same sample.
- Microscope Integration: Compatible with MetaMorph, MicroManager, NIS Elements, Zen, LAS X, cellSens, ImagePro.
Frequently Asked Questions
Yes, the CoolLED pE-4000 has an internal function generator for electrophysiology and optogenetics applications, and it also has TTL and USB interfaces with major imaging software packages that allow incorporation into all experimental parameters.
The CoolLED pE-4000 allows for a choice of 256 wavelength combinations from 16 installed LEDs (365 nm-770 nm), and you can choose 1 of 4 wavelengths for each of 4 channels on the control pod.
The CoolLED pE-4000 benefits from sustainable Green technology and delivers enhanced irradiance at the sample plane with a significant reduction in energy consumption. It also allows for individual control of selected LED wavelengths, reduces background, and enables rapid switching between LED wavelengths.
The CoolLED pE-4000 is a universal Illumination System for fluorescence microscopy that has 16 selectable LED wavelengths across four channels that can be finely controlled and matched to the filters and fluorophores of almost any microscope.
The power consumption of the CoolLED pE-4000 varies depending on the number of wavelengths used. The standby power consumption is max 7 W, single wavelength is max 25 W, dual wavelength is max 44 W, triple wavelength is max 53 W, and quad wavelength is max 60 W.