The pE-340 fura is a cutting-edge LED illuminator specifically designed for Fura-2 ratiometric calcium imaging. Built upon the successful pE-300 Series platform, this illuminator offers a compact and cost-effective solution for both specialized and everyday fluorescence microscopy. By providing optimal excitation wavelengths at 340 nm and 380 nm, the pE-340 fura ensures high-precision, stable, and high-throughput imaging capabilities with video-rate time resolution.

In practical applications, the pE-340 fura has demonstrated its effectiveness in capturing detailed images of cardiac myocytes, or heart cells, loaded with Fura-2. These images, obtained by researchers Martin Bootman and Katja Rietdorf from The Open University, highlight the illuminator's ability to support synaptically-driven Ca2+ events at varying frequencies, showcasing its versatility and precision in live-cell imaging.

One of the standout features of the pE-340 fura is its rapid response time. Unlike traditional illumination systems that rely on mechanical switching, the pE-340 fura can be controlled via BNC TTL connections, allowing for precise illumination control in as little as 20 microseconds. This advancement significantly enhances the speed and accuracy of Fura-2 imaging, making it a valuable tool for researchers.

Our expertise in LED technology has enabled us to optimize the internal optics of the pE-340 fura for efficient transmission of the 340 nm wavelength. The system is also configurable to accept a specific UV-compatible 3mm liquid light guide, ensuring high transmission efficiency. For those requiring additional customization, an optional Universal Collimator is available to further enhance the system's performance.