Description
ProCellics™ Raman Analyzer with Bio4C® PAT Raman Software is an innovative Process Analytical Technology (PAT) platform designed to revolutionize the monitoring of cell cultures. This cutting-edge solution allows for in-line and real-time analysis, providing a seamless transition from process development to full-scale manufacturing. Unlike traditional methods that rely on indirect parameters such as temperature, pH, and dissolved oxygen, the ProCellics™ Raman Analyzer offers direct insights into critical process parameters (CPP) and critical quality attributes (CQA), which are essential for understanding the true state of cell cultures.
In the complex world of bioprocessing, having real-time access to CPPs and CQAs is invaluable. The ProCellics™ Raman Analyzer is specifically tailored to meet the needs of the bioprocessing industry, enabling the continuous monitoring of key components such as glucose, lactate, glutamate, and protein titer, among others. This real-time data acquisition facilitates a deeper understanding of the process, allowing for enhanced control and optimization. By integrating this technology, users can implement automated process control strategies, significantly reducing the risk of contamination and batch failures compared to traditional manual sampling methods.
The platform is designed with user-friendliness in mind, making it accessible to both Raman experts and those new to the technology. Its ease of use is complemented by comprehensive technical support and services, ensuring successful implementation and operation. The ProCellics™ Raman Analyzer is available in two configurations, providing flexibility to adapt to various manufacturing requirements. This adaptability ensures that the solution can address a wide range of monitoring needs, from initial process development stages to full-scale manufacturing operations.
ProCellics™ Raman Analyzer with Bio4C® PAT Raman Software
Specifications
Excitation Wavelength: | 785 nm |
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Laser Power: | 350 mW |
Raman Shift Range: | 1 – 4000 cm^-1 |
Special Attributes: | Portable |
Connectivity: | WiFi |
Weight: | 6 kg |
Electrical Power Source: | Not specified |
Product Key Features: | Straylight removal solution, One-Batch Calibration, Chemometrics Support, GMP compliant, full package solution including hardware and software suite |
Features
- Real-Time Monitoring: The ProCellics™ Raman Analyzer with Bio4C® PAT Raman Software allows for in-line and real-time measurement of critical process parameters (CPPs) and critical quality attributes (CQAs), enhancing process understanding from development to manufacturing.
- Comprehensive Parameter Coverage: Monitor a wide range of CPPs and CQAs, including glucose, lactate, glutamate, glutamine, ammonium, VCD, TCD, amino acids, protein titer, glycosylation, aggregates, HCP, and DNA.
- Process Improvement: Gain greater process understanding and optimization with real-time data, increasing control and reproducibility during process development phases.
- Process Automation: Reduce off-line sampling and manual feeding with an automated nutrient control loop strategy, minimizing contamination risks and batch failures.
- Easy-to-Use: Designed for the bioprocessing industry, the analyzer and software are user-friendly for both Raman experts and those unfamiliar with Raman technology and multivariate analytics.
- Easy-to-Implement: Supported by comprehensive technical support and services from experienced engineers and chemometric bioprocessing experts, ensuring successful implementation and use.
- Adaptable Configurations: Available in two configurations, the ProCellics™ Raman Analyzer is fully adaptable to manufacturing requirements, addressing a range of monitoring needs from process development to manufacturing.
- Risk Reduction: The platform reduces contamination risk and batch failures compared to manual sampling, contributing to time-savings and operator flexibility.
Applications
- Real-Time Monitoring: Monitor critical process parameters (CPPs) and critical quality attributes (CQAs) in-line and in real-time, from process development to manufacturing.
- Process Improvement: Enhance process understanding and optimization, increasing control and reproducibility during development phases.
- Process Automation: Reduce off-line sampling and manual feeding with an automated nutrient control loop strategy, minimizing contamination and batch failure risks.
- Easy-to-Use: Designed for both Raman experts and those unfamiliar with Raman technology, ensuring ease of use across team members.
- Easy-to-Implement: Supported by comprehensive technical support and services from experienced engineers and chemometric bioprocessing experts.
- Adaptable Configurations: Available in single channel and other configurations to meet diverse monitoring needs from process development to manufacturing.
Frequently Asked Questions
What are the benefits of using ProCellics™?
What does ProCellics™ Software offer?
What is ProCellics™ and what is it used for?
What is Raman spectroscopy and how does it work?
What parameters can ProCellics™ measure?
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